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The Nathan S. Kline Institute for Psychiatric Research

Christopher K. Cain, Ph.D.

Christopher K. Cain, Ph.D.

Research Scientist
Emotional Brain Institute
845-398-6560

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Christopher Cain received his BA in Neuroscience & Behavior from Wesleyan University in Middletown CT in 1995. Following that, he worked in the Behavioral Pharmacology departments of CytoTherapeutics Inc. (Providence, RI) and Neurogen Corporation (Branford, CT) for two years each. These positions mainly entailed testing novel drugs designed to treat pain, anxiety and memory impairments. In 2004, he received his PhD from UCLA's Interdepartmental Neuroscience Program, where he studied fear extinction with Dr. Mark Barad. In 2010, Dr. Cain completed his training as a post-doctoral fellow in Dr. Joseph LeDoux's laboratory at NYU's Center for Neural Science, where he studied a number of avoidance-related learning phenomena. Dr. Cain currently has a lab at the Nathan Kline Institute for Psychiatric Research and is a Research Assistant Professor at the NYU School of Medicine (Child & Adolescent Psychiatry).

Highlights/Achievements/Awards
  • Cota-Robles Fellow, Interdepartmental Neuroscience Program, UCLA, 1999
  • Pre-doctoral Ruth L. Kirschstein Institutional National Research Service Award (F31MH065809), NIMH, 2002-2004
  • Samuel Eiduson Student Lecturer, Interdepartmental Neuroscience Program, UCLA, 2003
  • Post-doctoral Ruth L. Kirschstein Institutional National Research Service Award (F32MH077458), NIMH, 2006-2009
  • NIH Exploratory/Developmental Research Grant Award (R21MH097125), NIMH, 2012-2015
Select Publications

Cain CK, LeDoux JE. 2007. Escape from fear: a detailed behavioral analysis of two atypical responses reinforced by CS termination. J Exp Psychol Anim Behav Process 33: 451-463.

Lazaro-Munoz G, LeDoux JE, Cain CK. 2010. Sidman instrumental avoidance initially depends on lateral and basal amygdala and is constrained by central amygdala-mediated Pavlovian processes. Biol Psychiatry 67: 1120-1127.

Lazzaro SC, Hou M, Cunha C, LeDoux JE, Cain CK. 2010. Antagonism of lateral amygdala alpha1-adrenergic receptors facilitates fear conditioning and long-term potentiation. Learn Mem 17: 489-493.

Cain CK, Sullivan GM, LeDoux JE. 2013. The Neurobiology of Fear and Anxiety: Contributions of Animal Models to Current Understanding. In Neurobiology of Mental Illness,  (ed. DS Charney, JD Buxbaum, P Sklar, EJ Nestler). Oxford University Press, New York.

McCue MG, LeDoux JE, Cain CK. 2014. Medial amygdala lesions selectively block aversive pavlovian-instrumental transfer in rats. Front Behav Neurosci 8: 329.