Dr. Guilfoyle has worked in the NMR field for over 30 years in both industry and academia. For the past 17 years, he has worked to develop, refine and apply advanced high-speed methods for measurement of brain structure and function. He has particular interest in the study of neuropsychiatric disorders using a combination of human and rodent models. Recent work has placed particular emphasis on magnetic resonance spectroscopy, which examines brain chemistry, and the impact of chemogenetic approaches on brain chemistry.
Guilfoyle DN, Gerum SV, Sanchez JL, Balla A, Sershen H, et al. Functional connectivity fMRI in mouse brain at 7T using isoflurane. Journal of neuroscience methods. 2013; 214(2):144-8. PMID:23376497, PMCID: PMC3644382.
Guilfoyle, D.N., Gerum, S., Hrabe, J. (2011): Murine diffusion imaging using snapshot interleaved EPI acquisition at 7T. Journal of Neuroscience Methods 199, 10-14. PMCID: PMC3112266.
Hrabe, J., Hrabetova, S., Segeth, K. (2004): A model of effective diffusion and tortuosity in the extracellular space of the brain. Biophysical Journal 87, 1606-1617. PMCID: PMC1304566.
Elahi S, Bachman AH, Lee SH, Sidtis JJ, Ardekani BA; Alzheimer's Disease Neuroimaging Initiative. Corpus callosum atrophy rate in mild cognitive impairment and prodromal Alzheimer's disease. J Alzheimers Dis. 2015;45(3):921-31
Bachman AH, Lee SH, Sidtis JJ, Ardekani BA. Corpus callosum shape and size changes in early Alzheimer's disease: a longitudinal MRI study using the OASIS brain database. J Alzheimers Dis. 2014;39(1):71-8.