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The Nathan S. Kline Institute for Psychiatric Research

Recent Highlights


NKI researchers authored well over 200 publications in 2016. These include a number of high profile papers in outstanding journals such as The American Journal of Psychiatry, Nature Neuroscience, Nature Reviews Neuroscience, Neuron, PNAS, Molecular Psychiatry, Neuropsychopharmacology, and Biological Psychiatry.


NKI is Home to Several of the Most Cited Researchers in Neuroscience

Three NKI principal investigators – F. Xavier Castellanos, Joseph LeDoux, and Michael Milham – appear on Clarivate Analytics (formerly a division of Thomson Reuters) 2016 list of Highly Cited Researchers, reflecting the top 1% most cited researchers in their field.


Joseph LeDoux Publishes Anxious, Receives Award

Emotional Brain Institute Director Dr. Joseph LeDoux’s book Anxious: Using the Brain to Understand and Treat Fear and Anxiety, received the 2016 William James Book Award from the American Psychological Association. This book also appears on Forbes’ list of “The Must-Read Brain Books of 2015”.

Dr. LeDoux is also the recipient of the 2016 Jean Marie Delwart Prize for Molecular and Cellular Mechanisms Underlying Mood.


NKI Researchers Edit Special Issues

Dr. Masuo Ohno (Dementia Research) edited a special issue of Brain Research Bulletin on the topic of “Alzheimer's secretase enzymes: Cell biology, regulation, function and therapeutic potential”.

Dr. Helena Hansen (Social Solutions & Services) was co-guest editor of a special issue of the Journal of Bioethical Inquiry on the topic of “Structural Competency”.


Distinguished NKI Scientist Receives Hungarian State Honor

Dr. Abel Lajtha (Neurochemistry) was presented with the Order of Merit of Hungary, Officer’s Cross. The award ceremony was held on May 6 in Budapest, and the medal was presented by the Hungarian Foreign Minister, Péter Szijjártó.


NKI-Rockland Sample Project Passes Milestone

The NKI-Rockland Sample project enrolled its 1,500th research participant. Researchers from over 100 collaborating centers have accessed de-identified data collected at NKI through data usage agreements and have published over 120 scientific papers based on the NKI-Rockland Sample data.



Pioneering Research into the Early Brain Changes Recognized with Alzheimer's Association Science Award

Ralph A. Nixon, MD, PhD, Director of the Center for Dementia Research at NKI, was recognized for his “pioneering research into the early brain changes associated with Alzheimer´s disease, including the abnormal breakdown of proteins” by the Alzheimer´s Association with the Zaven Khachaturian Award for his achievement in advancing the field of Alzheimer´s disease science. This work has helped identify new avenues for investigating potential Alzheimer´s disease therapies.


Study Reveals Specific Protein as Missing Link Responsible for Earliest Known Change in Alzheimer’s Disease Pathology

A study conducted at Nathan S. Kline Institute for Psychiatric Research (NKI) and NYU Langone Medical Center implicates a new culprit in Alzheimer´s disease development. The research reveals that ßCTF -- the precursor of the amyloid beta (Aß) peptide -- acts at the earliest stage of Alzheimer´s to initiate a range of abnormalities leading to the loss of groups of neurons critical for memory formation. 


MERIT award from National Institute of Child Health and Human Development (NICHD)

Regina Sullivan, PhD, a member of the NKI Emotional Brain Institute, received a MERIT award from the National Institute of Child Health and Human Development (NICHD). MERIT stands for Method to Extend Research in Time, and these prestigious awards are given to investigators who have demonstrated superior competence and outstanding productivity during their previous research experience. Dr. Sullivan is the third NKI Researcher to receive a MERIT award from the National Institutes of Health.


Childhood Abuse May Be Paradoxically Protective in Adulthood

A group led by NKI investigator Regina Sullivan, PhD, used an animal model to show that reminders of early life abuse can actually help to reduce depression-like behaviors in adulthood. According to the authors, "Our findings suggest that infant trauma cues share properties with antidepressants and safety signals and provide insight into mechanisms by which infant trauma memories remain powerful throughout life." The results were published recently in the Proceedings of the National Academy of Sciences. The researchers also analyzed this phenomenon at the molecular level, demonstrating that the effect of the trauma cues are directly related to the levels of serotonin and corticosterone in the amygdala.


Ruane Prize for Outstanding Achievement in Child & Adolescent Research

Xavier Castellanos, MD , Director of Child & Adolescent Psychiatry Research, has been selected by the Brain Behavior Foundation for his efforts directed at the understanding of the neurobiology of ADHD. The Outstanding Achievement Prizes are among the most prestigious awards in the field of psychiatric research.  


NAMI-NYS Excellence in Research Award

NKI Research Scientist, Dr. Mary Jane Alexander, received the 2015 NAMI-NYS Excellence in Research Award. The award acknowledges her work investigating how to improve the public mental health system, eliminate barriers to treatment for people living with mental illness and advance recovery from trauma.



NKI Researcher Receives Wiley Young Investigator Award in Human Brain Mapping

Michael Milham, MD, PhD, received the 2014 Wiley Young Investigator Award in Human Brain Mapping. This award is given by the publisher Wiley in association with the Organization for Human Brain Mapping (OHBM), to recognize someone under the age of 40 who has made significant contributions to the field of human brain mapping


Presidential Early Career Award to NKI Scientist

Nathan Kline Institute research scientist Young Shin Kim, MD, MS, MPH, PhD, received the Presidential Early Career Award for Scientists and Engineers. This prestigious award is the highest honor bestowed by the United States Government on science and engineering professionals in the early stages of their independent research careers.


Dr. Joseph LeDoux to Receive Lifetime Achievement Award from the Association for Psychological Science

Joseph LeDoux, director of the Emotional Brain Institute and Professor in the NYU departments of Psychology, Psychiatry, and Child & Adolescent Psychiatry, has been named a recipient of the 2015 APS William James Fellow Award by the Association of Psychological Science (APS). This award honors APS Members for their lifetime of significant intellectual contributions to the basic science of psychology.


NKI Researchers in the top 1% of Number of Citations

Michael Milham, MD, PhD, F. Xavier Castellanos, MD each received recognition as Highly Cited Researchers (top 1% most cited for Neuroscience and Behavior) by Thomas Reuters 


Max Mozell Award for Outstanding Achievement in the Chemical Senses

NKI Research Scientist, Donald Wilson, PhD, received the 2014 Max Mozell Award for Outstanding Achievement in the Chemical Senses. This award is given by the Association for Chemoreception Sciences to recognize the accomplishments of a senior scientist working in the chemical senses with a research record of excellence and contributions that have had a major impact on research in the chemical senses. 


NAMI Bestows Honors

The National Alliance on Mental Illness - New York State (NAMI-NYS) presented the Nathan S. Kline Institute its Legislative Research Award in recognition of the Institute’s excellence in conducting cutting edge research into mental Illness.

The National Alliance on Mental Illness – Familya of Rockland County awarded NKI its Florence Gross Award for the Institute’s commitment to excellence in research.



Joseph LeDoux Elected to the National Academy of Sciences

Joseph LeDoux, PhD, a senior research scientist at NKI and director of the NKI/NYU Emotional Brain Institute, "in recognition of his distinguished and continuing achievements in original research”, was elected to the National Academy of Sciences.  This is one of the highest honors in science.


New Study places NKI in the top 1% of Research Institutions Worldwide

An analysis published in the Journal of the American Society for Information Science and Technology , ranked the Nathan S. Kline Institute for Psychiatric Research among the very best research facilities in the world. The study, which utilized an “excellence rate” of an institution’s publications  as an indicator of institutional impact placed NKI in the top 1% of institutions worldwide, along with only 29 others.  


Two NKI Researchers receive American Psychiatric Association´s 2013 Award for Research

The American Psychiatric Association´s 2013 Award for Research was given to four recipients whose collaborative efforts have advanced the development of pharmacological agents that can improve the lives of individuals with schizophrenia. Two of the four awardees are Nathan Kline Institute scientists -- Donald Goff, MD, NKI´s Director, and Daniel Javitt, MD, PhD, Director of Schizophrenia Research. Drs. Goff and Javitt have played a major role in altering the direction of drug development in schizophrenia, focusing on cognitive impairments and negative symptoms.


Cahn Research Award 

Stephen Ginsberg, PhD   received the Margaret M. Cahn Research Award   from the Hudson Valley/Rockland/Westchester Chapter of the Alzheimer’s Association. This award is presented in recognition of an Alzheimer’s Association-funded researcher in the New York area who is doing outstanding work.  


Second NKI Scientist Receives Prestigious National Institute of Mental Health (NIMH) Award

Cameron Craddock, PhD was named a recipient of an NIMH  Biobehavioral Research Award for Innovative New Scientists (BRAINS) becoming the second NKI Scientist to receive this award.  The BRAINS award is intended to support the research and research career development of outstanding scientists who are in the early, formative stages of their careers and who plan to make a long term career commitment to research in specific mission areas of the NIMH.